Orientia Tsutsugamushi

Bacterium Orientia Tsutsugamushi Budding From Its Host Cell Peritoneal Mesothelial Cell, Colorized Tem. This Specimen Comes From The Peritoneal Cavity Of A Mouse Infected Experimentally To Diagnose The Infection Of A Patient. Other Bacteria Are Visible In The Cytoplasm. Orientia Tsutsugamushi, Formerly Known As Rickettsia Tsutsugamushi, Is A Bacterium Responsible For Scrub Typhus Or Japanese Flood Ever. It Is A Gram Negative Bacillus, Intracellular Exclusively, That Proliferates Into The Cytoplasm Of The Macrophages, Dthe Endothelial Cells And The Polynuclear Neutrophils ; Therefore It Provokes Its Own Phagocytosis Through Those Cells, Then Live Freely In The Cytoplasm, Then Exit The Host Cell By Budding. Scrub Typhus Is A Disease Characterized By A High Fever 40°C, Cephalgias, Coughs, Obnubilations And An Adenopathy. This Zoonose Is Endemic In Eastern Asia And Western Pacific. It Is Transmitted Through Wild Rodents, That Are Its Reservoir, To Mankind By A Sting Of Trombiculidae Larvae From The Genus Leptotrombidium. Orientia Tsutsugamushi > Orientia > Rickettsie > Rickettsiaceae > Rickettsiales > Proteobacteria > Bacterium. This 1976 Transmission Electron Micrograph Tem Depicted A Hypertrophic Peritoneal Mesothelial Cell Of Mouse That Had Been Experimentally Infected Intraperitoneally With Orientia Tsutsugamushi Rickettsial Micro Organisms. This Micrograph Showed One Organism As It Was In The Process Of Budding From The Luminal Cell Surface, Still Covered By A Third Layer, Consisting Of The Host Cell's Plasma Membrane. Others Are Visible Free Within The Host Cell's Cytoplasm. Scrub Typhus Is An Acute Febrile Disease Caused By Orientia Tsutsugamushi. The Disease Occurs Mainly In The Large Triangular Region Extending From Japan In The North, To Australia In The Southwest, And The South Pacific Islands In The Southeast. Humans Are Infected By The Bite Of The Larva Of Th (Photo By BSIP/UIG Via Getty Images)